Speaker: Wesley Hamilton (UNC-Chapel Hill)
Title: Proteins and Persistence
Speaker's URL: https://www.whamilton.us/
Abstract: Protein fold classification is a classic problem in structural biology and bioinformatics. In this talk, I’ll present on recent work using persistent homology to quantify and understand the space of protein data objects. We compare quantifications based on persistent homology to other knot-theoretic quantifications, and show that persistence picks out something quantitatively different using the AJIVE statistical tool. I’ll also present on ongoing work incorporating ideas from multi parameter persistence to the analysis of protein structure. This is joint work with J.S. Marron, J.E. Borgert, and T. Hamelryck.
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